TAK1 converts Sequestosome 1p62 from an autophagy receptor to

Purified anti-p62 Antibody - p62 vom p62 is essential for the selective autophagy of protein aggregates , forming liquid-liquid phase separated condensates p62 p62 vom p62 contains an LC3-interacting region and is believed to be a substrate for selective autophagy In addition, p62 contains a domain that binds ubiquitin chains

p62 vom The autophagy receptor p62 plays an active role in the aggregation of ubiquitinated proteins The co-aggregation of p62 and ubiquitinated